Detalles de la búsqueda
1.
Population Dynamics and Structural Effects at Short and Long Range Support the Hypothesis of the Selective Advantage of the G614 SARS-CoV-2 Spike Variant.
Mol Biol Evol;
38(5): 1966-1979, 2021 05 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33386849
2.
Genomic Signature of Shifts in Selection in a Subalpine Ant and Its Physiological Adaptations.
Mol Biol Evol;
37(8): 2211-2227, 2020 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32181804
3.
Design of Disruptors of the Hsp90-Cdc37 Interface.
Molecules;
25(2)2020 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31952296
4.
The human DNA topoisomerase I mutant Gly717Asp: Higher religation rate is not always associated with camptothecin resistance.
Arch Biochem Biophys;
663: 165-172, 2019 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30653963
5.
Computational Analysis of Dengue Virus Envelope Protein (E) Reveals an Epitope with Flavivirus Immunodiagnostic Potential in Peptide Microarrays.
Int J Mol Sci;
20(8)2019 Apr 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-31003530
6.
Tyr120Asp mutation alters domain flexibility and dynamics of MeCP2 DNA binding domain leading to impaired DNA interaction: Atomistic characterization of a Rett syndrome causing mutation.
Biochim Biophys Acta Gen Subj;
1862(5): 1180-1189, 2018 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-29428602
7.
Chemo-enzymatic synthesis of (E)-2,3-diaryl-5-styryl-trans-2,3-dihydrobenzofuran-based scaffolds and their in vitro and in silico evaluation as a novel sub-family of potential allosteric modulators of the 90 kDa heat shock protein (Hsp90).
Org Biomol Chem;
16(20): 3741-3753, 2018 05 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-29722782
8.
Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads.
Chemistry;
23(22): 5188-5192, 2017 Apr 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-28207175
9.
Mutation of Gly717Phe in human topoisomerase 1B has an effect on enzymatic function, reactivity to the camptothecin anticancer drug and on the linker domain orientation.
Biochim Biophys Acta;
1854(8): 860-8, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25910424
10.
Human topoisomerase IB is a target of a thiosemicarbazone copper(II) complex.
Arch Biochem Biophys;
606: 34-40, 2016 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27431056
11.
Simulations of DNA topoisomerase 1B bound to supercoiled DNA reveal changes in the flexibility pattern of the enzyme and a secondary protein-DNA binding site.
Nucleic Acids Res;
42(14): 9304-12, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25056319
12.
Characterization of the differences in the cyclopiazonic acid binding mode to mammalian and P. Falciparum Ca2+ pumps: a computational study.
Proteins;
83(3): 564-74, 2015 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-25581715
13.
The human topoisomerase 1B Arg634Ala mutation results in camptothecin resistance and loss of inter-domain motion correlation.
Biochim Biophys Acta;
1834(12): 2712-21, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24096022
14.
Geometrical constraints limiting the poly(ADP-ribose) conformation investigated by molecular dynamics simulation.
Biopolymers;
101(1): 78-86, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23666795
15.
Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico.
Mol Cancer;
12(1): 100, 2013 Sep 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-24004603
16.
A derivative of the natural compound kakuol affects DNA relaxation of topoisomerase IB inhibiting the cleavage reaction.
Arch Biochem Biophys;
530(1): 7-12, 2013 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23262316
17.
ATP independent type IB topoisomerase of Leishmania donovani is stimulated by ATP: an insight into the functional mechanism.
Nucleic Acids Res;
39(8): 3295-309, 2011 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-21186185
18.
SARS-CoV-2 multi-variant rapid detector based on graphene transistor functionalized with an engineered dimeric ACE2 receptor.
Nano Today;
48: 101729, 2023 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-36536857
19.
Interaction between natural compounds and human topoisomerase I.
Biol Chem;
393(11): 1327-40, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23109546
20.
Evidences of a natively unfolded state for the human topoisomerase IB N-terminal domain.
Amino Acids;
41(4): 945-53, 2011 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-21046176